Carbidopa 38821-49-7

Item Code:38821-49-7 Features:EP/USP
  • Description
Product: Carbidopa
Other name: Benzenepropanoic acid,α-hydrazino-3,4-dihydroxy-α-methyl-,monohydrate(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
Structure:
Formula: C10H14N2O4,H2O
Molecular weight: 244.2
CAS No.: 38821-49-7
Quality Standards: Ph. Eur/USP
Characteristics: A white or yellowwish-white powder,slightly soluble in water,very slightly soluble in slcohol,practically insoluble in methylene chloride.It dissolves in dilute solutions of mineral acids.
Packing: 25kg/drum

    

Items

Standards

 

Description

A white or creamy-white powder

 

Solubility

Slightly soluble in water, freely soluble in 3N hydrochloric acid; slightly soluble in methanol; practically insoluble in alcohol, in acetone, in chloroform, and in ether.

 

Identification

IR

IR spectrum is consistent with carbidopa CRS

 

HPLC

Conform with the retention time of the major peak in the chromatogram

 

Specific rotation

-21.0°~-23.5°

 

Loss on drying

6.9% ~ 7.9%

 

Residue on ignition

0.1% max

 

Heavy metal

0.001% max

 

-Methyldopa

0.5% max

 

-Carbidopa related components A

0.5% max

 

-Any unknown impurity

0.10% max

 

-Total impurities

1.0%max

 

Residual solvents

Meet the requirement

 

Assay

98.0%~102.0%

 

 

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